CATALYTIC PARTICLES FOR INCREASED SENSITIVITY IN LATERAL FLOW IMMUNOASSAYS
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United States of America Patent
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Mar 9, 2017
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Mar 9, 2016
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Abstract
The present invention provides a method for preparing colloidal palladium nanoparticles and using them for increased sensitivity in lateral flow immunoassays. Glutaraldehyde is used in preparing the colloidal palladium that allows rapid attachment of biomolecules. Colloidal palladium nanoparticles are labeled with a protein, such as a biomolecule or an antibody. These labeled colloidal palladium particles catalytically develop a dye to detect the presence of an analyte.
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