Methods and systems for three-dimensional real-time intraoperative surgical margin evaluation of tumor tissues

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United States of America Patent

PATENT NO 10325366
APP PUB NO 20180053298A1
SERIAL NO

15730996

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Abstract

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A method of evaluating a surgical margin of tumor tissues of a living subject includes acquiring images of a specimen of the tumor tissues; calculating a three-dimensional (3D) morphological surface of the specimen from the acquired images and displaying the 3D morphological surface; obtaining, from the 3D morphological surface, a plurality of specimen locations to cover a surface of the specimen; acquiring optical data at each specimen location; evaluating a margin status of the specimen at each specimen location to either positive or negative based on the acquired optical data; and displaying the margin status of the specimen on the 3D morphological surface of the specimen with morphological orientations.

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Patent Owner(s)

  • BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY AND VANDERBILT UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bi, Xiaohong Nashville, US 3 25
Gowani, Zain Nashville, US 2 24
Holt, Ginger Nashville, US 2 5
Mahadevan-Jansen, Anita Nashville, US 45 1304
Nguyen, John Pomona, US 113 4451
Nguyen, The-Quyen Evanston, US 3 15
Pence, Isaac Crestwood, US 3 27

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