Anti-IL-25 antibodies and uses thereof

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United States of America Patent

PATENT NO 10640558
APP PUB NO 20180057583A1
SERIAL NO

15805584

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides antibodies that bind to human interleukin-25 (IL-25) and methods of using the same. According to certain embodiments, the antibodies of the invention bind human IL-25 with high affinity. In certain embodiments, the invention includes antibodies that bind human IL-25 and block IL-25-mediated cell signaling. The antibodies of the invention may be fully human, non-naturally occurring antibodies. The antibodies of the invention are useful for the treatment of various disorders associated with IL-25 activity or expression, including asthma, allergy, chronic obstructive pulmonary disease (COPD), inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, atopic dermatitis (AD), and Eosinophilic Granulomatosis with Polyangiitis (EGPA), also know as Churg-Strauss Syndrome.

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Patent Owner(s)

Patent OwnerAddress
REGENERON PHARMACEUTICALS INC777 OLD SAW MILL RIVER ROAD TARRYTOWN NY 10591-6707

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allinne, Jeanne New York, US 7 27
Orengo, Jamie M Cortlandt Manor, US 32 198

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