Digital Analysis of Circulating Tumor Cells in Blood Samples

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United States of America Patent

SERIAL NO

15560324

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This disclosure relates to new assay methods for analysis of circulating tumor cells (CTCs) in blood samples for detection, e.g., early detection, and/or monitoring of disease, e.g., cancer. The methods provide ultra-high sensitivity and specificity, and include the use of microfluidic isolation of CTCs and digital detection of RNA derived from the CTCs.

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Patent Owner(s)

Patent OwnerAddress
THE GENERAL HOSPITAL CORPORATION55 FRUIT STREET BOSTON MA 02114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Haber, Daniel A Chestnut Hill, US 40 970
Hong, Xin Medford, US 79 1843
Javaid, Sarah Cambridge, US 2 1
Kapur, Ravi Sharon, US 97 5786
Maheswaran, Shyamala Lexington, US 23 29
Miyamoto, David Tomoaki Wellesley, US 4 2
Todorova, Tanya Malden, US 5 3
Toner, Mehmet Charlestown, US 170 6581

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