Method of preparing sample for analysis and analysis method

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United States of America Patent

PATENT NO 10712338
APP PUB NO 20180059094A1
SERIAL NO

15562698

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Abstract

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In the method of preparing a sample for analysis, a reaction is performed that produces different modified product depending on the sialic acid linkage type when a sialic acid is bound to a sugar chain of an analyte. In this reaction, an analyte containing a sugar chain, an amine containing two or more carbon atoms, and a dehydration-condensation agent are used. The sialic acid linkage type can be identified by analyzing the resulting sample with mass spectrometry etc. This method is applicable not only to free sugar chains but also to glycopeptides and glycoproteins.

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Patent Owner(s)

  • SHIMADZU CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nishikaze, Takashi Kyoto, JP 15 6

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