MAGNETIC NANOSTRUCTURE FOR DETECTING AND ISOLATING CIRCULATING TUMOR CELLS COMPRISING ANTIBODY- AND MAGNETIC NANOPARTICLE-CONJUGATED CONDUCTIVE POLYMER

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United States of America Patent

SERIAL NO

15246615

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Abstract

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Disclosed is a magnetic nanostructure for detecting and isolating circulating tumor cells including a conductive polymer to which an antibody and magnetic nanoparticles are bound, which enables circulating tumor cells from early cancer patients and various circulating tumor cell types to be effectively detected using a small amount of blood, circulating tumor cells to be monitored with the naked eye through colorimetric detection, and a very small amount of circulating tumor cells present in blood to be efficiently captured with a strong magnetic field generated by a large amount of the loaded magnetic nanoparticles; in detecting, isolating, and collecting the circulating tumor cells in a very small amount, a long nanowire structure and various antibody types are used, whereby contact with cancer cells may be increased and strong bonding may be formed; sensitivity is increased and various interactions with cancer cells are facilitated, thereby exhibiting increased detection and isolation effects.

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Patent Owner(s)

Patent OwnerAddress
GENOPSY CO LTD102-5-HO 2F 427 TEHERAN-RO GANGNAM-GU SEOUL 06159

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHO, Youngnam Goyang-si, KR 9 24
HONG, Wooyoung Goyang-si, KR 2 5
LEE, Eun Sook Goyang-si, KR 20 31

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