SALTS AND CRYSTALLINE FORMS OF AN APOPTOSIS-INDUCING AGENT

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United States of America Patent

APP PUB NO 20180065961A1
SERIAL NO

15806964

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Abstract

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Salts and crystalline forms of 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}-sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide are suitable active pharmaceutical ingredients for pharmaceutical compositions useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.

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Patent Owner(s)

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ABBVIE INC1 NORTH WAUKEGAN ROAD NORTH CHICAGO IL 60064

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Catron, Nathaniel Vernon Hills, US 11 99
Chen, Shuang Gurnee, US 61 1923
Gong, Yuchuan Waukegan, US 23 362
Zhang, Geoff G Vernon Hills, US 23 37

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