COMPOSITIONS AND METHODS FOR INTRAVITREAL DELIVERY OF POLYNUCLEOTIDES TO RETINAL CONES

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United States of America Patent

SERIAL NO

15554664

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Abstract

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Methods and compositions are provided for intravitreally delivering a polynucleotide to cone photoreceptors. Aspects of the methods include injecting a recombinant adeno-associated virus comprising a polynucleotide of interest into the vitreous of the eye. These methods and compositions find particular use in treating ocular disorders associated with cone dysfunction and/or death.

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Patent Owner(s)

Patent OwnerAddress
ADVERUM BIOTECHNOLOGIES INC800 SAGINAW DR REDWOOD CITY CA 94063

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chalberg, Thomas W Redwood City, US 9 42
Neitz, Jay Seattle, US 30 219
Neitz, Maureen Seattle, US 28 197

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