BRUTON'S TYROSINE KINASE INHIBITOR COMBINATIONS AND USES THEREOF
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United States of America Patent
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Jul 21, 2017
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Aug 8, 2014
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Abstract
Disclosed herein are methods, compositions, and kits for treating a B-cell malignancy comprising administering a combination of a BTK inhibitor (e.g. ibrutinib) and a PIM inhibitor. Also disclosed herein are methods, compositions, and kits for treating a BTK-resistant B-cell malignancy comprising administering a combination of a BTK inhibitor (e.g. ibrutinib) and a PIM inhibitor.
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