F-labelled folates as PET radiotracers

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United States of America Patent

PATENT NO 10961246
APP PUB NO 20180072734A1
SERIAL NO

15711316

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Abstract

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The present invention is directed towards new 18F-folate radiopharmaceuticals, wherein fluorine-18 is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of therapy of cancer and inflammatory and autoimmune diseases.

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Patent Owner(s)

Patent OwnerAddress
MERCK & CIE8200 SCHAFFHAUSEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ametamey, Simon Mensah Zurich, CH 13 31
Groehn, Viola Dachsen, CH 51 182
Moser, Rudolf Schaffhausen, CH 64 360
Muller, Cristina Magdalena Nussbaumen, CH 6 14
Ross, Tobias Ludwig Zurich, CH 7 18
Schibli, Roger Baden, CH 40 236

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