Nucleic acid sequencing by nanopore detection of tag molecules

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United States of America Patent

PATENT NO 11608523
APP PUB NO 20180073071A1
SERIAL NO

15712763

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Abstract

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This disclosure provides systems and methods for sequencing nucleic acids using nucleotide analogues and translocation of tags from incorporated nucleotide analogues through a nanopore. In aspects, this disclosure is related to compositions, methods, and systems for sequencing nucleic acids using tag molecules and detection of translocation through a nanopore of tags released from incorporation of the molecule.

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Patent Owner(s)

  • COLUMBIA UNIVERSITY/THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK; ROCHE SEQUENCING SOLUTIONS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Roger Saratoga, US 97 2802
Davis, Randall Pleasanton, US 51 646
Ju, Jingyue Englewood Cliffs, US 128 6559

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