Method for reconstructing aspergillus niger to increase citrate production

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United States of America Patent

PATENT NO 10618940
APP PUB NO 20180194814A1
SERIAL NO

15868136

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Abstract

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The invention discloses a method for increasing citrate production from genome reconstructed Aspergillus niger. The method is to insert a gene of low affinity glucose transporter, LGT1, to genome of A. niger. The expression level of LGT1 is under control of promoter Pgas. The genome reconstructed A. niger is tolerant to higher fermentation temperature and lower pH than that of the parental strain. Moreover, the production, yield and purity of product from reconstructed A. niger are higher than that of parental strain, and the fermentation time is shorter.

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Patent Owner(s)

  • JIANGNAN UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Jian Wuxi, CN 1536 22502
Du, Guocheng Wuxi, CN 65 8
Hu, Zhijie Wuxi, CN 3 0
Jiang, Jianwei Wuxi, CN 4 0
Jiang, Xiaodong Wuxi, CN 12 2
Jin, Sai Wuxi, CN 3 0
Li, Jianghua Wuxi, CN 36 49
Liu, Long Wuxi, CN 59 35
Sun, Fuxin Wuxi, CN 3 0
Yin, Xian Wuxi, CN 5 0
Zhang, Cheng Wuxi, CN 317 3054

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