Thyroglobulin quantitation by mass spectroscopy

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United States of America Patent

PATENT NO 10191064
APP PUB NO 20180196062A1
SERIAL NO

15906078

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Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.

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Patent Owner(s)

  • QUEST DIAGNOSTICS INVESTMENTS INCORPORATED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clarke, Nigel J Oceanside, US 70 655
Reitz, Richard E San Clemente, US 91 1017
Zhang, Yanni Mission Viejo, US 18 188

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