Functionally-modified oligonucleotides and subunits thereof

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United States of America Patent

PATENT NO 10344281
APP PUB NO 20180223278A1
SERIAL NO

15700718

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Abstract

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Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.

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Patent Owner(s)

  • SAREPTA THERAPEUTICS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cai, Bao Zhong Corvallis, US 11 305
Hanson, Gunnar J Bothell, US 198 1233
Weller, Dwight D Corvallis, US 77 7172
Zhou, Ming Coppell, US 279 4977

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