Systems and methods for high-accuracy variant calling

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United States of America Patent

PATENT NO 11393557
APP PUB NO 20180237949A1
SERIAL NO

15755095

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Abstract

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Systems and methods for in silico prediction of HLA type of a patient are presented in which patient sequence reads and a reference sequence with known and distinct HLA alleles are used in a de Bruijn graph. A composite match score is then used to rank HLA alleles, thus providing a first HLA type. A second HLA type is identified by re-ranking using an adjusted composite match score.

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Patent Owner(s)

Patent OwnerAddress
NANTOMICS LLC9920 JEFFERSON BOULEVARD CULVER CITY CA 90232

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sanborn, John Zachary Santa Cruz, US 85 527

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