Multi-layer airway organoids and methods of making and using the same

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United States of America Patent

PATENT NO 11001811
APP PUB NO 20180291350A1
SERIAL NO

15768100

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Abstract

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Provided herein are artificial lung organoids. The artificial lung organoids may include an epithelial cell layer comprising mammalian lung epithelial cells, a stromal cell layer comprising mammalian lung fibroblast cells and an endothelial cell layer comprising mammalian endothelial cells. The artificial lung organoids may optionally include a porous membrane between said epithelial cell layer and said stromal cell layer and/or between said stromal cell layer and said endothelial lung cell layer.

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Patent Owner(s)

  • WAKE FOREST UNIVERSITY HEALTH SCIENCES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Atala, Anthony Winston-Salem, US 161 5495
Murphy, Sean V Winston-Salem, US 7 43

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