QUANTITATIVE ASSESSMENT FOR CAP EFFICIENCY OF MESSENGER RNA

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United States of America Patent

APP PUB NO 20180291425A1
SERIAL NO

15936293

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Abstract

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The present invention provides, among other things, methods of quantitating mRNA capping efficiency, particularly for mRNA synthesized in vitro. In some embodiments, the methods comprise chromatographic methods of quantifying capping efficiency and methylation status of the caps.

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Patent Owner(s)

Patent OwnerAddress
TRANSLATE BIO INC29 HARTWELL AVENUE LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DeRosa, Frank Cambridge, US 237 2201
Dias, Anusha Cambridge, US 54 250
Heartlein, Michael Cambridge, US 206 2431

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