TRANSCRIPTOMIC INDEX FOR CHARACTERIZING THE CELLULAR REPAIR RESPONSE AFTER SOFT TISSUE INJURY IN DIARTHRODIAL JOINTS

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United States of America Patent

APP PUB NO 20180291455A1
SERIAL NO

15974941

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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One aspect of the invention provides methods for classifying the quality of a repair response after injury to a joint of a subject. In one embodiment, the method includes providing a tissue sample from the injured region of the joint and determining expression levels in the sample of a plurality of genes, including at least those genes listed in Table 1, Table 2 and Table 3. Another aspect of the invention provides methods of treating a human or veterinary subject having an injury to a joint based on the classification of the quality of the repair response.

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Patent Owner(s)

Patent OwnerAddress
RUSH UNIVERSITY MEDICAL CENTER1653 WEST CONGRESS PARKWAY ATTN IP OFFICE CHICAGO IL 60612

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chan, Deva Chicago, US 4 4
Li, Jun Chicago, US 1261 16348
Plaas, Anna HK Chicago, US 4 2
Sandy, John D Chicago, US 6 19
Wang, Vincent Chicago, US 19 83

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