CYTOTOXIC T CELL RESPONSE MODIFIERS

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United States of America Patent

APP PUB NO 20180298388A1
SERIAL NO

16004077

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Abstract

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The present invention relates to a compound selectively binding to a sensory receptor or selectively altering the expression of a sensory receptor for use in a method for treating or preventing a disease associated with a pathologic cellular cytotoxic T cell (CTL) response. Further, the invention relates to means for detecting a sensory receptor for use in a method for diagnosing cellular resistance against CTL response in a patient. The invention further embraces a method for determining the resistance of a cell against a CTL response in vitro and to a method for identifying agents that influence the response of cells to CTLs.

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Patent Owner(s)

Patent OwnerAddress
DEUTSCHES KREBSFORSCHUNGSZENTRUMIM NEUENHEIMER FELD 280 HEIDELBERG 69120

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beckhove, Philipp Heidelberg, DE 15 5
Boutros, Michael Heidelberg, DE 20 59
Breinig, Marco Bad Rappenau, DE 8 0
Khandelwal, Nisit Heidelberg, DE 16 0

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