Multiparticulate L-carnitine compositions and related methods
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United States of America Patent
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Jun 23, 2020
Grant Date -
Dec 27, 2018
app pub date -
Sep 4, 2018
filing date -
Jun 7, 2011
priority date (Note) -
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Abstract
An oral controlled-release multiparticulate dosage form comprises a plurality of individually enteric coated particulates containing an L-carnitine that independently disperse in a patient's stomach after oral ingestion and travel through the stomach and past the pyloric sphincter without substantially releasing the L-carnitine in the stomach. The individual particulates contain (a) a solid core containing the L-carnitine, (b) a subcoating containing a cellulosic water soluble polymer over the core, and (c) an enteric coating over the subcoating. The dosage form may be used to treat conditions associated with a reduction of the amount of L-carnitine in the body.
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