TARGETING THE HDAC2-SP3 COMPLEX TO ENHANCE SYNAPTIC FUNCATION

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Jan 17, 2019
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Jul 12, 2018
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Jul 12, 2018

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Abstract

The present disclosure provides, in some embodiments, methods for treating a neurodegenerative disease in a subject using a histone deacetylase 2 (HDAC2)/Sp3 inhibitor, which may be a peptide inhibitor comprising the carboxyl-terminus of HDAC2, and related compositions.

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MASSACHUSETTS INSTITUTE OF TECHNOLOGY	77 MASSACHUSETTS AVE CAMBRIDGE MA 02139

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Inventor Name	Address	# of filed Patents	Total Citations
Cheng, Jemmie	Elmsford, US	1	0
Gao, Fan	Cambridge, US	21	19
Penney, Jay	Malden, US	1	0
Tsai, Li-Huei	Cambridge, US	51	475
Yamakawa, Hidekuni	Cambridge, US	3	0

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TARGETING THE HDAC2-SP3 COMPLEX TO ENHANCE SYNAPTIC FUNCATION

Number of patents in Portfolio can not be more than 2000

United States of America Patent

16033635

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16033635

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