Compositions and methods for treating cancer with DuoCARs

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United States of America Patent

PATENT NO 10689431
APP PUB NO 20190083596A1
SERIAL NO

16134735

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Novel therapeutic immunotherapy compositions comprising at least two vectors, each vector encoding a functional CAR, whereby the combination of vectors results in the expression of two or more non-identical binding domains, wherein each vector encoded binding domain(s) are covalently linked to a transmembrane domain and one or more non-identical intracellular signaling motifs are provided herein as well as are methods of use of same in a patient-specific immunotherapy that can be used to treat cancers and other diseases and conditions.

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Patent Owner(s)

  • LENTIGEN TECHNOLOGY INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dropulic, Boro Ellicott City, US 73 169
Haso, Waleed M Fair Lawn, US 8 32
Miltenyi, Stefan Bergisch Gladbach, DE 80 1006
Orentas, Rimas J Seattle, US 45 105
Schneider, Dina Potomac, US 49 67

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