Acetalanthraquinone derivatives useful for cellular staining

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United States of America Patent

PATENT NO 11447638
APP PUB NO 20190249011A1
SERIAL NO

16312652

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Abstract

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The present invention provides di-substituted acetalanthraquinone-based compounds of the Formulae (l)-(IV) that are useful for cellular staining and for light-based detection of biological material, e.g. fluorescence-based detection of biological material. These compounds may be used in hydrolysed or non-hydrolysed form. Also provided is a fluorescent complex that comprises a nucleic acid and an acetalanthraquinone-based compound of the invention; and a method of staining a biological sample comprising cells or other biological material containing nucleic acid, which method comprises contacting the biological sample with an acetalanthraquinone-based compound of the invention. In the Formulae (l)-(IV), A and B are each independently of formula —RaCH2CH(ORb)2; or one of A and B is of formula —RaCH2CH(ORb)2 and the other one is of formula: —NRb2.

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Patent Owner(s)

Patent OwnerAddress
BIOSTATUS LIMITEDLEICESTERSHIRE LE129NP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cosentino, Laura Philadelphia, US 1 0
Errington, Rachel Jane Rhoose South Glamorgan, GB 7 81
Patterson, Laurence Hylton Skipton, GB 16 47
Pors, Klaus Shipley, GB 4 0
Smith, Paul James Cowbridge South Glamorgan, GB 49 538

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