SYSTEMS AND METHODS FOR ALTERING MICROBIOME TO REDUCE DISEASE RISK AND MANIFESTATIONS OF DISEASE
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United States of America Patent
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Aug 22, 2019
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Jan 22, 2019
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Aug 1, 2016
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Abstract
The present invention relates to the microbiomes of humans and other animals as biomarkers and therapeutic targets for regulation or altering of a microbiome profile associated with states of disease or disease risk, using additive and subtractive therapies aimed at restoring a microbiome profile associated with health, with reduced manifestations of disease, or with reduced disease risk. In particular, the invention provides methods of subtractive therapy using microorganism-specific avian egg yolk-derived immunoglobulins (IgY) in a fashion that titrates, without necessarily eliminating, populations of microorganisms known to be associated with human gut and extraintestinal diseases.
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