METHOD FOR PROCESSING POLYNUCLEOTIDE-CONTAINING SAMPLES

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20190338344A1
SERIAL NO

16518735

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Abstract

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Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.

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Patent Owner(s)

Patent OwnerAddress
HANDYLAB INC1 BECTON DRIVE FRANKLIN LAKES NJ 07417

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Althaus, John S Saline, US 23 965
Brahmasandra, Sundaresh N Ann Arbor, US 60 5505
Haley, Cecelia Canton, US 12 849
Handique, Kalyan Ann Arbor, US 224 14268
Kehrer, Aaron Ypsilanti, US 33 1661
Parunak, Gene Saline, US 64 3816
Phadke, Nikhil Ann Arbor, US 22 1655
Springer, Ted Ann Arbor, US 7 502
Wu, Betty Canton, US 35 2720

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