BIOMEDICAL PATCHES WITH ALIGNED FIBERS

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20200000570A1
SERIAL NO

16540335

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Abstract

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A three-dimensional electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a flexible deposited fiber network of varying density including a first and second set of set of electrospun fibers. The second set of electrospun fibers is coupled to the first. A first portion of the flexible deposited fiber network includes a higher density of fibers than a second portion of the flexible deposited fiber network, and the tensile strength of first portion is higher than that of the second portion. The scaffold is sufficiently flexible to facilitate application of scaffold to uneven surfaces of the tissue substrate, and enables movement of the scaffold by the tissue substrate. The first and second set of fibers are configured to degrade within three months after application, and each fiber of the deposited fiber network has a diameter of 1-1000 nanometers.

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Patent Owner(s)

Patent OwnerAddress
WASHINGTON UNIVERSITYONE BROOKINGS DRIVE ST LOUIS MO 63130

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
MacEwan, Matthew R St. Louis, US 14 13
Ray, Zack St. Louis, US 5 8
Xia, Younan St. Louis, US 46 1623
Xie, Jingwei St. Louis, US 14 15

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