BIOMATERIAL BASED ON ALIGNED FIBERS, ARRANGED IN A GRADIENT INTERFACE, WITH MECHANICAL REINFORCEMENT FOR TRACHEAL REGENERATION AND REPAIR

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20200015962A1
SERIAL NO

16570510

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An implant can include a plurality of polymeric fibers associated together into a fibrous body. The fibrous body is capable of being shaped to fit a tracheal defect and capable of being secured in place by suture or by bioadhesive. The fibrous body can have aligned fibers (e.g., circumferentially aligned) or unaligned fibers. The fibrous body can be electrospun. The fibrous body can have a first characteristic in a first gradient distribution across at least a portion of the fibrous body. The fibrous body can include one or more structural reinforcing members, such as ribbon structural reinforcing members, which can be embedded in the plurality of fibers. The fibrous body can include one or more structural reinforcing members bonded to the fibers with liquid polymer as an adhesive, the liquid polymer having a substantially similar composition of the fibers.

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Patent Owner(s)

  • THE UNIVERSITY OF KANSAS; CHILDREN'S MERCY HOSPITAL

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Detamore, Michael Lawrence, US 14 51
Ott, Lindsey Lawrence, US 2 2
Weatherly, Robert Overland Park, US 2 2

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