USE OF SUBSTITUTED BENZYLIDENEGUANIDINE DERIVATIVES AS SYNERGISTS FOR POLYMYXIN ANTIBIOTICS
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United States of America
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Jan 16, 2020
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Mar 30, 2016
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Mar 30, 2016
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Abstract
A use of a substituted benzoguanidine derivative as a polymyxin antibiotic synergist, particularly as a synergist and a drug resistance reversal agent of the polymyxin antibiotic for inhibiting a sensitive strain, or a composition comprising the same in combination with a polymyxin antibiotic for preparing a compound pharmaceutical preparation for human or animal use in the treatment of a disease caused by a gram-negative bacterial infection or the preparation a growth-promoting feed additive and for the raising of livestock animals.
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