METHOD FOR ACTIVATING AND EXPANDING ISOLATED T CELLS

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20200017830A1
SERIAL NO

16583264

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Abstract

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A method for activating and expanding isolated T cells, the method including adding to isolated T cells ligands presenting microbubbles having a flexible lipid shell with an inner bubble wall enclosing a gas and an outer bubble wall conjugated to ligands capable of achieving cell contact dependent juxtacrine signaling on the isolated T cells; and adding to isolated T cells ligands presenting microbubbles having a flexible lipid shell with an inner bubble wall enclosing a gas and an outer bubble wall conjugated to an antigen capable of forming an immunological synapse (IS) with the T cells.

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Patent Owner(s)

Patent OwnerAddress
DIAGNOLOGIX LLC5820 OBERLIN DRIVE STE 104 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Kimberly San Diego, US 4 10
Shi, Guixin San Diego, US 9 18
Wang, Ying-Ting San Diego, US 2 10

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