Importance

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Abstract

Methods of producing and isolating ⁶⁸Ga, ⁸⁹Zr, ⁶⁴Cu, ⁶³Zn, ⁸⁶Y, ⁶¹Cu, ^99mTc, ⁴⁵Ti, ¹³N, ⁵²Mn, or ⁴⁴Sc and solution targets for use in the methods are disclosed. The methods of producing ⁶⁸Ga, ⁸⁹Zr, ⁶⁴Cu, ⁶³Zn, ⁸⁶Y, ⁶¹Cu, ^99mTc, ⁴⁵Ti, ¹³N, ⁵²Mn, or ⁴⁴Sc include irradiating a closed target system with a proton beam. The system can include a solution target. The methods of producing isolated ⁶⁸Ga, ⁸⁹Zr, ⁶⁴Cu, ⁶³Zn, ⁸⁶Y, ⁶¹Cu, ^99mTc, ⁴⁵Ti, ⁵²Mn, or ⁴⁴Sc further include isolating ⁶⁸Ga, ⁸⁹Zr, ⁶⁴Cu, ⁶³Zn, ⁸⁶Y, ⁶¹Cu, ^99mTc, ⁴⁵Ti, ⁵²Mn, or ⁴⁴Sc by ion exchange chromatography. An example target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window.

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First Claim