SENSOR FOR NADP (H) AND DEVELOPMENT OF ALCOHOL DEHYDROGENASES

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20200027049A1
SERIAL NO

16518544

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Abstract

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The present invention relates to an NADP(H) nanosensor comprising

    i) a nucleic acid sequence to which a regulator is capable of binding, wherein the oxidation state of the regulator depends on the NADP(H) availability;ii) a promoter sequence following the nucleic acid sequence i), to which an RNA polymerase is capable of binding, wherein the affinity of the RNA polymerase for the promoter sequence is influenced by the oxidation state of the regulator;iii) a nucleic acid sequence which is under the control of the promoter sequence ii) and which codes for an autofluorescent protein.

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Patent Owner(s)

Patent OwnerAddress
FORSCHUNGSZENTRUM JULICH GMBHWILLIAM JOHN STREET ULRICH GERMANY HAUSACH BADEN-WURTTEMBERG

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BINDER, Stephan Eschweiler, DE 8 25
BOTT, Michael Julich, DE 22 44
BRINGER-MEYER, Stephanie Julich, DE 5 17
EGGELING, Lothar Julich, DE 55 377
SCHENDZIELORZ, Georg Dusseldorf, DE 3 6
SIEDLER, Solvej Aachen, DE 8 1

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