TRANSIENT DISRUPTION OF THE BLOOD-RETINAL BARRIER OF A HUMAN AND USES THEREOF FOR TREATING A RETINA DISORDER

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20200046556A1
SERIAL NO

16609385

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to an ultrasound contrast agent for use in treating a retina disorder by transiently disrupting the blood-retinal barrier (BRB) of a human, wherein the ultrasound contrast agent is administered just before and/or during the application, to the retina of the human, of an unfocused ultrasound (US) beam. The present invention further relates to a therapeutically active agent for use in treating a retina disorder in a human, wherein the therapeutically active agent is to be delivered in combination with an ultrasound contrast agent, which is administered before and/or during the application, to the retina of the human, of an unfocused ultrasound (US) beam in order to transiently disrupting the blood-retinal barrier (BRB) of the human, to allow the therapeutically active agent to cross the BRB and to target the retina. The present invention also relates to an eye ultrasound delivery device that may be used to treat a retina disorder.

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Patent Owner(s)

Patent OwnerAddress
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS3 AVENUE VICTORIA PARIS 75004
SORBONNE UNIVERSITE21 RUE DE L'ÉCOLE DE MÉDECINE PARIS 75006

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carpentier, Alexandre Paris, FR 21 742

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