HLA-INDEXED REPOSITORY OF iPSCS AND iPSC-DERIVED STEM CELLS, AND RELATED SYSTEMS AND METHODS

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20200051666A1
SERIAL NO

16492690

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Abstract

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Described herein is a managed, indexed repository of hematopoietic stem cell (HSC) lines and/or blood progenitor cell lines derived from induced pluripotent stem cells (iPSCs) (or embryoid bodies formed from iPSCs), wherein each of the HSC lines, blood progenitor cell lines, embryoid bodies, and/or iPSC lines has corresponding data comprising a set of characterized HLA loci, said corresponding data being stored in a searchable database for retrieval of one or more matching physical cell lines upon query. The repository comprises an HLA-indexed bank of iPSCs, embryoid bodies, HSCs, and/or blood progenitor cells for each of a set of HLA types, for identification and provision of allogeneic cell lines suitable for transplantation to reestablish hematopoietic function in patients with damaged, diseased, or otherwise abnormal bone marrow and/or immune system.

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Patent Owner(s)

Patent OwnerAddress
ORIG3N INC27 DRYDOCK AVE 6TH FLOOR BOSTON MASSACHUSETTS 02210 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Glicksman, Marcie A Boston, US 23 149
Smith, Robin Y Boston, US 23 84

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