NON-HUMAN ANIMALS HAVING A HUMANIZED PROGRAMMED CELL DEATH 1 GENE

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20200053992A1
SERIAL NO

16673119

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Non-human animals, and methods and compositions for making and using the same, are provided, wherein the non-human animals comprise a humanization of a Programmed cell death 1 (Pdcd1) gene. The non-human animals may be described, in some embodiments, as having a genetic modification to an endogenous Pdcd1 gene so that the non-human animals express a PD-1 polypeptide that includes a human portion and an endogenous portion (e.g., a non-human portion).

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Patent Owner(s)

Patent OwnerAddress
REGENERON PHARMACEUTICALS INC777 OLD SAW MILL RIVER ROAD TARRYTOWN NY 10591-6707

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burova, Elena Mount Kisco, US 16 58
Lai, Ka-Man Venus San Francisco, US 56 546
Mujica, Alexander O Elmsford, US 20 300
Murphy, Andrew J Croton-on-Hudson, US 338 2697

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