MAPPING PROTEIN BINDING SITES AND CONFORMATIONAL EPITOPES USING CYSTEINE LABELLING AND SURFACE DISPLAY LIBRARY

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United States of America

APP PUB NO 20200072850A1
SERIAL NO

16467229

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Abstract

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The present disclosure provides a rapid, scalable, and high-throughput method of identifying the precise regions in a receptor protein which are involved in binding of a molecule of interest. The method of the instant disclosure is useful where the crystal structure of a protein of interest is not available. Also provided are surface display libraries, and methods of making the same.

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Patent Owner(s)

Patent OwnerAddress
INDIAN INSTITUTE OF SCIENCEOFFICE OF INTELLECTUAL PROPERTY AND TECHNOLOGY LICENSING BANGALORE 560012

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Datta, Rohini Bangalore, IN 1 0
Najar, Tariq Ahmad Bangalore, IN 1 0
Varadarajan, Raghavan Bangalore, IN 5 4

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