Electrical sensing, tracking, and actuation of droplets

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United States of America Patent

PATENT NO 11440007
APP PUB NO 20200101456A1
SERIAL NO

16150059

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Devices, techniques, and processes are disclosed that use electrical impedance to detect of the presence and contents of droplets including cells, nucleic acids, proteins, or solute concentrations in an array of retrievable, trackable, trapped droplets in a fluidic system. Electrodes may be positioned underneath individual droplet traps in a microchannel to assay droplet contents and/or actuating droplets for the release of the droplets from corresponding traps. The disclosed technology may be used for detection of the results of solvent extraction processes including time-dependent quantification of metal ion concentration in the aqueous and organic phases, for wastewater treatment, heavy metal detection, pharmaceutical industry, and/or biotechnology, or for environmental monitoring of wastewater for toxic metal, monitoring of biological cell viability and proliferation, monitoring of extraction processes used in heavy metal mining, monitoring of extraction processes used in nuclear fuel processing, monitoring kinetics of enzyme processes, and/or assessing pharmacodynamics and drug efficacy.

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Patent Owner(s)

Patent OwnerAddress
LAWRENCE LIVERMORE NATIONAL SECURITY LLC7000 EAST AVENUE LIVERMORE CA 94550

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beer, N Reginald Pleasanton, US 35 554
Simon, Melinda Fremont, US 6 7
Watkins, Nicholas Brentwood, US 12 47

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