Method for producing retinal tissue and retina-related cells
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United States of America Patent
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Oct 18, 2022
Grant Date -
Apr 2, 2020
app pub date -
Nov 22, 2019
filing date -
Aug 23, 2013
priority date (Note) -
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Abstract
The present invention provides a method for producing a retinal progenitor cell, including (1) a first step of subjecting pluripotent stem cells to floating culture in a serum-free medium to form an aggregate of pluripotent stem cells, and (2) a second step of subjecting the aggregate formed in step (1) to floating culture in a serum-free medium or serum-containing medium each being free of a substance acting on the Sonic hedgehog signal transduction pathway but containing a substance acting on the BMP signal transduction pathway, thereby obtaining an aggregate containing retinal progenitor cells.
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