THERMORESPONSIVE COMPOSITIONS AND METHODS FOR PREVENTING AND DISRUPTING BIOFILMS
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United States of America
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Apr 15, 2021
app pub date -
Mar 21, 2019
filing date -
Mar 21, 2019
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Abstract
One aspect of the present disclosure can include a thermoresponsive nanocomposite for disrupting or preventing biofilm formation. The nanocomposite can include at least one polymer, one or more D-amino acids, and one or more energy-actuatable particles. The nanocomposite can have a first viscosity at about room temperature and, when exposed to about physiological temperature, obtains a second viscosity that is greater than the first viscosity. Application of energy to the nanocomposite from an energy source can excite the one or more energy-actuatable particles to cause localized heat release from the nanocomposite.
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