Multiple Heteroresistance to Guide Combination Antibiotic Regimens
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United States of America Patent
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Nov 11, 2021
app pub date -
Sep 23, 2019
filing date -
Sep 21, 2018
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Abstract
This disclosure contemplates detecting antimicrobial heteroresistance to guide antibiotic or other antimicrobial therapy. In certain embodiments, this disclosure contemplates avoiding a monotherapy with antibiotics to which an individual bacterial pie isolate is heteroresistant, because this can lead to treatment failure. Thus, in certain embodiments, one uses a combination of antibiotics to which a bacterium is individually heteroresistant.
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