METHOD FOR EXTRACTING ASTRAGALOSIDE IV FROM FRESH RADIX ASTRAGALI

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United States of America

APP PUB NO 20220024969A1
SERIAL NO

17380871

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Abstract

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The disclosure discloses a method for extracting Astragaloside IV from fresh Radix Astragali. The method comprises the following steps: cleaning and cutting fresh Radix Astragali roots into sections, and extracting with an ethanol solution for multiple times under an ultrasonic condition; merging the extracting solutions, concentrating to remove ethanol, hydrolyzing the concentrate with sodium hydroxide-calcium hydroxide mixed alkali, filtering the precipitate; then flocculating and precipitating by using a flocculating agent chitosan, and filtering; removing impurities through a flocculation-precipitation mode and filtering with a filter screen; separating through a macroporous adsorption resin, and finally purifying through recrystallization to obtain a high-purity Astragaloside IV. The method has the advantages of easily available raw materials, low cost, high Astragaloside IV extraction efficiency, high Astragaloside IV purity and simple process, the raw materials involved in the extraction process are non-toxic and harmless, and it is suitable for large-scale industrial production.

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Patent Owner(s)

Patent OwnerAddress
SHANXI UNIVERSITY030006 NO 92 HOLLYWOOD ROAD TAIYUAN SHANXI TAIYUAN CITY SHANXI PROVINCE 030006
FUKANGLIHUA (SHANXI) BIOLOGICAL TECHNOLOGY CO LTDA623 BUILDING A ENTERPRISE INCUBATION BUILDING CUSTOMS CLEARANCE SERVICE CENTER TAIYUAN 030006

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HUANG, Yuejun Taiyuan, CN 5 47
PAN, Jigang Taiyuan, CN 1 0
ZHANG, Jun Lake Forest, US 1152 7034

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