POWDER COMPOSITION COMPRISING A COPOLYMER MIXTURE AND A WATER-SOLUBLE CELLULOSE
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United States of America Patent
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Issued Date -
Aug 18, 2022
app pub date -
Jun 8, 2020
filing date -
Jun 13, 2019
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Abstract
A powder composition contains 50 to 95% by weight of a copolymer mixture A of a copolymer 1 and a copolymer 2, and 50 to 5% by weight of a water-soluble cellulose B. The copolymer 1 contains 5 to 60% by weight of polymerized units of methacrylic acid and 95 to 40% by weight of C1- to C4-alkylesters of (meth)acrylic acid. The copolymer 2 contains more than 95 and up to 100% by weight of polymerized units of C1- to C4-alkylesters of (meth)acrylic acid. The powder composition originates from the co-processing of the copolymer mixture A and the water-soluble cellulose B by a drying process of an aqueous dispersion, such as spray drying or freeze drying. Further processing leads to a compressed dosage form.
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