CONVERGENT LIQUID PHASE SYNTHESES OF OLIGONUCLEOTIDES

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United States of America Patent

APP PUB NO 20220348602A1
SERIAL NO

17608802

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure describes a convergent liquid phase process for manufacturing oligonucleotides by coupling two or more oligonucleotide fragments, each of which have two or more nucleotides. Also provided by the present disclosure are reaction steps involved the convergent liquid phase process.

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Patent Owner(s)

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AJINOMOTO CO INCTOKYO 104-8315

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Antia, Firoz Cambridge, US 2 0
Fillon, Yannick Cambridge, US 3 0
Gronke, Robert S Cambridge, US 11 32
Hamagaki, Takuya Kawasaki, JP 1 0
Ichimaru, Taisuke Kawasaki, JP 11 27
Jiang, Hong Cambridge, US 548 6417
Kiesman, William F Cambridge, US 18 51
Nguyen, Hien Cambridge, US 96 4737
Shi, Xianglin Cambridge, US 13 32
Takahashi, Daisuke Kawasaki, JP 266 1309
Yan, Wuming Cambridge, US 8 48
Zhou, Xuan Cambridge, US 67 122

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