A VIRAL EXPOSURE SIGNATURE FOR DETECTION OF EARLY STAGE HEPATOCELLULAR CARCINOMA

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United States of America Patent

APP PUB NO 20230003730A1
SERIAL NO

17766015

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Abstract

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A viral exposure signature (VES) that can identify early stage, pre-symptomatic hepatocellular carcinoma (HCC) among at-risk patients is described. The VES was developed using serological profiling and synthetic virome technology to identify unique viral peptide epitopes corresponding to 61 viral species. Methods of identifying a subject with early stage (pre-symptomatic) HCC using the VES are described.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES6011 EXECUTIVE BOULEVARD SUITE 325 MSC 7660 OFFICE OF TECHNOLOGY TRANSFER NATIONAL INSTITUTES OF HEALTH BETHESDA MD 20892-7660

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Jinping Wynnewood, US 60 134
Tang, Wei Bethesda, US 217 3421
Wang, Xin Wei Rockville, US 18 75

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