BILE ACID-GCPII INHIBITOR CONJUGATES TO TREAT INFLAMMATORY DISEASES, INCLUDING INFLAMMATORY BOWEL DISEASE (IBD)

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United States of America Patent

APP PUB NO 20230128984A1
SERIAL NO

17795426

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Abstract

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GCPII inhibitors comprising 2-(phosphonomethyl) pentanedioic acid (2-PMPA) conjugated to a bile acid and their use for treating a disease or condition associated with elevated levels of GCPII, including inflammatory bowel disease.

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INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR V V I16610 PRAHA 6

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Majer, Pavel Prague, CZ 38 153
Peters, Diane E Baltimore, US 2 1
Rais, Rana Baltimore, US 30 60
Slusher, Barbara Baltimore, US 45 104
Snajdr, Ivan Prague, CZ 8 6
Tenora, Lukas Prague, CZ 15 35

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