VECTOR LIBRARY FOR YEAST TWO HYBRID SCREENING AND METHOD FOR IDENTIFYING DEUBIQUITINATING ENZYME BINDING TO TARGET PROTEIN USING SAME

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United States of America Patent

APP PUB NO 20230272555A1
SERIAL NO

18315532

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Abstract

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Provided is a vector library for yeast two-hybrid screening of a deubiquitinating enzyme that binds to a target protein and a method for identifying a deubiquitinating enzyme binding to a target protein using the same. Further provided is a method for screening an agent having anti-cancer activity targeting the deubiquitinating enzyme USP1, USP7, USP12, or USP49 identified by the identifying method.

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Patent Owner(s)

Patent OwnerAddress
CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION120 HAERYONG-RO POCHEON-SI GYEONGGI-DO 11160

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BAEK, Kwang-Hyun Seoul, KR 41 638
KIM, So-Ra Gimcheon-si, KR 52 1442
KIM, Soo-Yeon Chuncheon-si, KR 7 12
KWON, Seul-Ki Seongnam-si, KR 2 0
LEE, Da-Hye Seoul, KR 2 0

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