SCALED-UP METHODS FOR PURIFYING ANTIBODIES
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United States of America Patent
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Issued Date -
May 2, 2024
app pub date -
Apr 16, 2020
filing date -
Aug 22, 2019
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Abstract
A method of isolating an antibody is disclosed. The method comprises contacting a hydrophobic chelator, a non-ionic detergent and metal ions so as to generate an aggregate comprising the hydrophobic chelator, the detergent and the metal ions; and contacting the aggregate with a medium comprising the antibody under conditions that allow partitioning of the antibody into the aggregate. Kits for isolating the antibody are also disclosed.
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