CANNABIS PREVENTS NK INACTIVATION IN CANCER AND INCREASES NK FUNCTION

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United States of America Patent

APP PUB NO 20240148809A1
SERIAL NO

18025499

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Abstract

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The present invention provides methods for increasing NK cytotoxicity of natural killer (NK) cells by administering to a subject in need thereof a composition comprising cannabis in an amount effective to induce apoptosis of a tumor cell. This invention also provides methods for increasing or restoring secretion of interferon gamma (IFN-γ) by a peripheral blood mononuclear cell (PMBC), in particular an NK cell, by administering to a subject in need thereof a composition comprising cannabis. The present invention further provides methods for preventing or reversing inactivation of cytotoxicity of an NK cell by administering to a subject in need thereof a composition comprising cannabis in an amount effective to induce apoptosis of a tumor cell. Methods for treating a subject having cancer or a tumor by administering a composition comprising cannabis are provided.

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Patent Owner(s)

Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA1111 FRANKLIN STREET 5TH FLOOR OAKLAND CA 94607-5200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jewett, Anahid Los Angeles, US 14 23
Ryan, Tracy Sherman Oaks, US 4 52

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