Complexes Of CU(I) As Antitumor Agents

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United States of America Patent

APP PUB NO 20240239814A1
SERIAL NO

18569713

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Abstract

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The invention relates to a Cu(1) complex of Formula (I), wherein L is a ligand of Formula (II), wherein n1, n2, n3 are independently to each other, an integer from 0 to 1, A1, A2 and A3 are independently from each other,—a phenyl optionally substituted with (C1-C3)alkoxy, (C1-C3)alkyl, F, formyl, carboxyl, sulphonyl hydroxyl, hydroxyl, methoxy(C1-C3)alkoxy or—an heterocyclic ring selected from piperazinyl, morpholynyl, thiomorpholynyl, optionally substituted with (C1-C3)alkyl, where the heterocyclic ring is linked with the nitrogen atom to —CH2— residue, with the proviso that when A1, A2 or A3 is optionally substituted phenyl, then n1, n2 or n3, respectively, is 0, and when A1, A2 or A3 is optionally substituted heterocyclic ring, then n1, n2 or n3, respectively, is 1, for use in the treatment of tumours.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITA' DEGLI STUDI DI PADOVA35122 PADOVA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gandin, Valentina Tarzo, IT 4 2
Marzano, Cristina Padova, IT 4 2
Porchia, Marina Padova, IT 5 2
Tisato, Francesco Padova, IT 9 16

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