MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS

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United States of America Patent

APP PUB NO 20240239828A1
SERIAL NO

18586086

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Abstract

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Compounds and compositions that have a mannose 6-phosphate receptor or ASGPR binding ligand bound to an extracellular protein binding ligand are provided for the selective degradation of a target extracellular protein in vivo to treat disorders mediated by the extracellular protein.

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Patent Owner(s)

Patent OwnerAddress
AVILAR THERAPEUTICS INC400 TOTTEN POND ROAD SUITE 110 WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grau, Daniel Arlington, US 6 162
Karra, Srinivasa Pembrooke, US 22 93
Ray, Soumya Quincy, US 25 166
Wiles, Jason Allan Madison, US 102 2022

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