MOLECULAR PROBES FOR IN VIVO DETECTION OF ALDEHYDES

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United States of America Patent

APP PUB NO 20240285808A1
SERIAL NO

18290135

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Abstract

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Disclosed herein are methods of molecular magnetic resonance (MR) imaging and positron emission tomography using extracellular probes that target extracellular allysine aldehyde and act as a noninvasive biomarker of fibrogenesis with high sensitivity and specificity in detecting fibrogenesis, for example, in rodent models and human fibrotic tissues.

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Patent Owner(s)

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THE GENERAL HOSPITAL CORPORATION55 FRUIT STREET BOSTON MA 02114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akam, Eman Somerville, US 1 0
Caravan, Peter Cambridge, US 19 91
MA, Hua Somerville, US 18 68
Ning, Yingying Somerville, US 2 0
Shuvaev, Sergey Somerville, US 3 0

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